The news comes after Senator John McCain (R-Ariz.) released a statement that he would miss this week's votes as he recovers from surgery.
"Elaine and I, along with the entire Senate family, wish John the very best and wish him a speedy recovery," McConnell's statement read. "While John is recovering, the Senate will continue our work on legislative items and nominations and will defer consideration of the Better Care Act."
McCain's absence meant Senate Republicans almost certainly would not have had the 50 votes needed to win a procedural vote this week.
McCain underwent a procedure to remove a blood clot from his eye on Friday, according to statements from his office and the Mayo Clinic. He is recovering at home in Arizona.
Sens. Rand Paul (R-Ky.) and Susan Collins (R-Maine) have already said they would oppose the procedural vote. With all Democrats voting no, that would leave Republicans with just 49 votes, given McCain's absence.
The further delay in the schedule is expected to hurt Senate Republicans, as opponents of the legislation use the extra time to pressure wavering GOP centrists to vote against it.
The healthcare bill was already on rocky ground even with McCain, as many speculated whether McConnell could pull together 50 votes.
McConnell announced this week he was extending the Senate's sessions for two weeks, cutting the August recess short. That could give his conference more time to get healthcare done.
This is the second time a vote on the bill has been delayed. The original vote was postponed from late June until after the July 4th recess.
McCain, 80, had the procedure done at the Mayo Clinic Hospital in Phoenix following an annual physical.
"Senator McCain received excellent treatment at Mayo Clinic Hospital in Phoenix, and appreciates the tremendous professionalism and care by its doctors and staff," a statement from his office said.
Photo Credit : © Provided by The Hill McConnell delays healthcare vote after McCain surgery